Melanocortin Receptor Research
Studied as a melanocortin receptor agonist, with published work focusing particularly on MC3R and MC4R signaling.
Overview
Melanocortin receptor and central signaling research.
PT-141, commonly known in the scientific literature as bremelanotide, is a synthetic cyclic heptapeptide derived from melanocortin peptide research. Its ring-constrained structure distinguishes it from linear melanocortin peptides and has made it a useful molecular probe for studying melanocortin-receptor signaling.
Published research characterizes PT-141 as a melanocortin receptor agonist with particular activity involving MC3R and MC4R. These receptors are expressed in the central nervous system and participate in signaling networks associated with autonomic, behavioral, neuroendocrine, and other centrally mediated physiological responses.
Experimental work has examined PT-141 in receptor pharmacology, neuronal activation, dose-response, pharmacokinetic, and central melanocortin signaling models. Suria lists the 10 mg research vial as Coming Soon while batch-specific analytical documentation is pending.
Research Use Only. Not for human or veterinary use.
Specifications
Molecular reference information.
- Common Research Names
- PT-141, bremelanotide
- Peptide Class
- Synthetic cyclic melanocortin peptide
- Peptide Length
- 7 amino-acid residues
- Condensed Sequence
- Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-OH
- Molecular Formula
- C50H68N14O10 (free base)
- Molecular Weight
- 1025.2 g/mol (free base)
- CAS Number
- 189691-06-3
- Structural Features
- Cyclic lactam peptide; N-terminal acetylation; D-phenylalanine residue
- Research Targets
- Melanocortin receptors, particularly MC3R and MC4R signaling
- Appearance
- Lyophilized research material
- Research Focus
- Melanocortin receptor pharmacology, central signaling, neuronal-response and receptor-activation models
- Availability
- 10 mg — Coming Soon
Certificate of Analysis
Product documentation.
Certificate of Analysis
PT-141 is not currently available for purchase. A certificate is published when a lot is released for sale.
Research Highlights
Why researchers study it.
Central Signaling Models
Used in experimental models examining centrally mediated melanocortin signaling and neuronal-response pathways.
Receptor Pharmacology
Its cyclic peptide structure and receptor activity make PT-141 useful in ligand-receptor, dose-response, and pharmacology research.
Pharmacokinetic Research
Published studies have characterized exposure, time-to-peak concentration, elimination, and dose-dependent response patterns.
Storage
Protect research material integrity.
Lyophilized material
Store cold, dry, and protected from direct light. Follow the handling requirements supplied with the released research lot.
Moisture and temperature
Minimize unnecessary temperature cycling and moisture exposure during laboratory storage and handling.
Batch documentation
Refer to the applicable batch documentation for lot-specific analytical and handling information once the product is released.
Research Use Only. Not for human consumption.
Frequently Asked Questions
PT-141 research reference.
What is PT-141?
PT-141, also known as bremelanotide, is a synthetic cyclic melanocortin peptide studied for its activity at melanocortin receptors, particularly MC3R and MC4R.
Is PT-141 available now?
Not yet. Suria's 10 mg PT-141 is listed as Coming Soon while batch-specific testing and review are completed.
Will a COA be available?
Yes. Applicable batch documentation will be posted after analytical testing is complete and the lot has passed Suria's release review.
Is this for human consumption?
No. Suria products are sold strictly for laboratory and scientific research use and are not intended for human or veterinary use.
Batch Documentation
View available analytical documentation for this research product.
View DocumentationRelated Research Compounds
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